cholesterol biosynthesis pathway
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FDFT1 mouse monoclonal antibody, clone OTI2F10 . Target: Homo sapiens farnesyl-diphosphate farnesyltransferase 1 (FDFT1), transcript variant 3. This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq]. Immunogen: Full length human recombinant protein of human FDFT1(NP_004453) produced in HEK293T cell. Buffer: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Explore: Association of high cholesterol levels with nerve spoil
Lipid profiles. METHODS: This about enrolled 136 patients with MS (n = 272 eyes. A subset of 88 patients received criterion reversal visual-evoked potential (PRVEP) testing
. 45% had a curriculum vitae of optic neuritis (ON). Subjects received optical coherence tomography (OCT) testing to assess RNFL thickness and visual acuity testing with Snellen charts.
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Schematic representation of the cholesterol biosynthesis pathway, with ...
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Several hydroxysterol compounds formed from cholesterolby ...