cholesterol biosynthesis pathway

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Recombinant Farnesyl Diphosphate Farnesyltransferase 1 (FDFT1) (Recombinant Protein)
Recombinant Farnesyl Diphosphate Farnesyltransferase 1 (FDFT1) (Recombinant Protein) by MyBioSource

  • FPP:FPP farnesyltransferase; presqualene-di-diphosphate synthase
  • GeneName: FDFT1; SS; SQS; DGPT; ERG9
  • FREE-8GB-USBDrive for this item. Item is for research use. NOT for...

Product Description
*Subcellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein@@Endotoxin Level: ; *Accession#: NP_004453.3; NM_004462.4; P37268; *Description: About the Marker: Effective Size Range: 10kDa to 70kDa.Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa.Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy.Ready-to-use: No need to heat, dilute or add reducing agents before use.; *NCBI Summary: This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008]; *Uniprot Summary: Catalytic activity: 2 farnesyl diphosphate + NAD(P)H = squalene + 2 diphosphate + NAD(P)+.Cofactor: Magnesium.Pathway: Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 1/3.Subunit structure: Monomer By similarity.Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Sequence similarities: Belongs to the phytoene/squalene synthase family.

Questions & answers

  1. Lud Lud says:
    is the cholesterol knock down in our blood directly related to the cholesterol content of our diet?
    Is this viewpoint generally accepted. Medical Association (April 21, 1999), seem to be compelling the position that the link between dietary and blood cholesterol is not particularly aggressive.
    Gina C says:
    There are a lot of factors on this one, and the channel one is that people would rather expect people to take a medicate and mind their specific food choices, than to trust them to admit defeat weight.

com/devicesupport. https://youtube.

  1. LKB1 and AMPK and the cancer-metabolism tie up - ten years after
    Thus, the LKB1-AMPK pathway may act as a tumor suppressor with the aid its ability to restrain the growth of pre-neoplastic lesions, but paradoxically may provoke established tumor cells more resistant to the metabolic stresses induced by biguanides or cytotoxic ...
  2. Lovastatin induces apoptosis from one end to the other the mitochondrial pathway in an undifferentiated SH-SY5Y neuroblastoma cell way
    ... that neurons are skilful to produce cholesterol 3 even if the mechanisms regulating this pathway remain unclear. The testimony that cholesterol biosynthesis deregulation is involved in neurodegenerative diseases gave new pertinacity to the studies focused on ...

Explore: Association of high cholesterol levels with nerve spoil

Lipid profiles. METHODS: This about enrolled 136 patients with MS (n = 272 eyes. A subset of 88 patients received criterion reversal visual-evoked potential (PRVEP) testing. 45% had a curriculum vitae of optic neuritis (ON). Subjects received optical coherence tomography (OCT) testing to assess RNFL thickness and visual acuity testing with Snellen charts.

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  1. Reconstruction of the biosynthetic pathway for the substance fungal polyketide ...
    Fungal polyketides classify commercially important pharmaceuticals and food additives, e.g. the cholesterol-lowering statins and the red and orange monascus pigments. Shortly, production relies on isolation of the compounds from the organically grown
  2. Using biology to take a new lease on life chemical synthesis
    One such aggravate, 3-hydroxyg-butyrolactone (3HBL), can be widely reach-me-down in the pharmaceutical industry as a chiral building shut off for the statin class of cholesterol-reducing drugs such as Crestor and Lipitor, as clearly as the antibiotic Zyvox, and the
  3. Chemistry of Disappearing The bottle: Your Body A Culprit or A Victim? - Body of knowledge 2.0
    Another decision by Min You, et al (2009) suggests that ethanol induces fatty acid merge pathway by activation of the Sterol RegulatoryElement-Binding Protein (SREBP). SREBP is a transcription cause that binds with DNA and can trigger the synthesis
  4. הדוקטור- פורטל בריאות ורפואה שמן קריל כנגד דלקות וארתריטיס
    Fresh risk factors for systemic atherosclerosis: a contrast of C-reactive protein, fibrinogen, homocysteine, lipoprotein(a), and guide cholesterol screening as predictors of peripheral arterial disorder. JAMA 285: leukotriene biosynthesis by the leukocyte upshot 15-hydroxy-5,8,11,13- eicosatetraenoic acid. J Biol Chem 255; Effects of exogenous arachidonic, eicosapentaenoic and docosahexaenoic acids on the epoch of 5-lipoxygenase pathway products by ionophore-activated individual neutrophils.
Schematic representation of the cholesterol biosynthesis pathway, with ...
Schematic representation of the cholesterol biosynthesis pathway, with ... - Figure - Figure
Several hydroxysterol compounds formed from cholesterolby ...
Several hydroxysterol compounds formed from cholesterolby ...