diabetes insipidus treatment

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Same information as on the web, but all in one place, this book., July 14, 2017
This is the same information that I have found on the web. The only advantage here is that it is in all one area, this book. That said, he is often repetitive, repeating the same sentence as the one immediately previous. Thirty-one percent of the...
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Diabetes Insipidus

What is Diabetes Insipidus?

Diabetes Insipidus is a rare disease which is characterized by the absence of antidiuretic hormone (ADH) resulting in a copious flow of dilute urine and excessive thirst.

Diabetes insipidus is a not common condition in which the kidneys are unable to prevent the excretion of water.

What is the Cause of Diabetes Insipidus?

During the day, the kidneys filter all the blood many times.

Normally, most of the water is reabsorbed, and only a small amount of concentrated urine is excreted.

Central Diabetes insipidus

Diabetes insipidus occurs when the kidneys cannot concentrate the urine normally, and a large amount of dilute urine is excreted.

The amount of water passed out in the urine is controlled by antidiuretic hormone (ADH).

ADH is also called vasopressin.

ADH is a hormone which is formed in a part of the brain called the hypothalamus.

The pituitary gland stores ADH in the posterior lobe and releases it when the body requires it.

The pituitary gland is a small organ at the base of the brain.

Diabetes insipidus resulting from a lack of ADH from the pituitary gland is called central diabetes insipidus.

Primary Central diabetes insipidus:

Primary Central diabetes insipidus forms 50% of Central diabetes insipidus and is due to the decrease of nuclei of the neurohypophyseal gland.

It has a genetic cause.

Secondary Central diabetes insipidus

Secondary Central diabetes insipidus can be caused by damage to the hypothalamus or pituitary gland as a result of:

a. Head injury
b. Infection
c. Loss of blood supply to the gland
d. Surgery
e. Tumor
f. Granuloma
g. Brain aneurysm or thrombosis
h. Histiocytosis

Nephrogenic Diabetes insipidus

When Diabetes insipidus is caused by a failure of the kidneys to respond to ADH, the condition is called nephrogenic diabetes insipidus.

Nephrogenic Diabetes insipidus occurs as a result from a defect in the kidneys.

Consequently the kidneys will not react to the effects of ADH.

Like central Diabetes insipidus, nephrogenic Diabetes insipidus is very rare.

Nephrogenic DI may be caused by:

1. Genetic problems – x-linked recessive genetic inheritance

Homozygous males are unresponsive to Antidiuretic Hormone

Heterozygous females have normal or impaired response to ADH

Secondary Nephrogenic DI may be caused by:

b. Certain drugs (such as lithium)

c. High level of calcium in the body (hypercalcemia)

d. Kidney disease (such as polycystic kidney disease)

Diabetes insipidus is an uncommon disturbance resulting from any condition damaging the neurophyseal system of pituitary gland.

It is idiopathic in 45 % of cases

It occurs at any age and affects either sex

It is unusual in infancy but can commence in early childhood

It is acquired from head trauma, neoplasm (primary and metastatic especially the breast), sarcoidosis, birth injuries or eosinophilic granuloma

What are the Symptoms of Diabetes Insipidus?

1. Polyuria- Excessive urine volume - Urine output 5-10 liters per 24 hours

Excessive urination, often needing to urinate every hour throughout the day and night

2. Polydipsia (especially for cold water)

Excessive thirst that may be intense or not controllable together with the need to drink large amounts of water or craving for ice water

3. No evidence of ill health

Urine volumes and abnormality in patients with head trauma and coma should be monitored



Chapter 1 Diabetes Insipidus

Chapter 2 Causes

Chapter 3 Symptoms

Chapter 4 Diagnosis

Chapter 5 Treatment

Chapter 6 Prognosis
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Questions & answers

  1. Juliette Juliette says:
    My two year old has just been diagnosed with diabetes insipidus any tips?
    Does anyone have a young gentleman with this and have any tips for me at all on how i can help her. My 2 year old little girls that has had on the spot sleeping has just been diagnosed with diabetes insipidus.
    J B says:
    Go to WebMd. From the start, you need to become as knowledgeable as you can very rapidly.
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How to Manage Diabetes Insipidus? - Keep Healthy Everyday

Verbal vasopressin invalid. Aqueous vasopressin with 5 ~ 10U subcutaneously, the r for 3 to 6 hours. (A) aqueous vasopressin the diabetes insipidus within reach hormone replacement therapy. Such agents are commonly hardened in a state of intoxication secondary to the initial treatment of patients with knowledge trauma or neurosurgery after the onset of diabetes insipidus.
Source: http://www.keephealthy24.com/%EF%BB%BFhow-to-treat-diabetes-insipidus/

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