Hyperlipidemia Complications

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Cardiovascular disease is the number one cause of death for men and women in this country, surpassing deaths due to all cancers combined. Better awareness of heart disease risk factors and improved treatment modalities has produced great progress in reducing deaths due to myocardial infarction and stroke over the past few decades.  Still, more progress is needed, as about half of all first coronary events occur in individuals who have no cardiac symptoms and no previously diagnosed heart disease.  The primary care physician, therefore, has an important role in identifying at risk individuals and beginning preventive modalities.   In Hyperlipidemia in Primary Care: A Practical Guide to Risk Reduction, a group of leading authorities in the field offers a comprehensive overview of the problem along with practical strategies for treating it.   This unique title reviews methods for assessing risk in patients, including an important and thorough discussion of the Framingham algorithm and its limitations and advantages in assessing CVD risk.    The book also reviews the evolving world of lipidology and how to apply many of the newer lipid tests to patients in daily practice, putting these tests into proper perspective and offering a rational approach to using them in practice.   Finally, treatment issues are covered.   As treatment has expanded to more risk groups, a number of different guidelines have been published with recommended lipid goals. This is an evolving area of research with rapidly changing guidelines that are expanding the pool of high risk patients.   An invaluable reference that offers a reasonable approach to risk assessment and treatment of individuals at increased cardiovascular risk, Hyperlipidemia in Primary Care: A Practical Guide to Risk Reduction provides the background needed to make scientifically based decisions that can ultimately help greatly reduce the number of patients impacted by cardiovascular  disease.
Product Description
The increased oxidative stress associated with diabetic patients is partly due to increased reactivity of the iron within the heme pocket of hemoglobin. Haptoglobin, a plasma protein, functions as an antioxidant by binding to hemoglobin and preventing it from initiating oxidative chain reactions. Haptoglobin has two alleles, 1 and 2, which form three different phenotypes that differ in their antioxidant capabilities. Haptoglobin 2–2 is inferior to Haptoglobin 1–1 as an antioxidant. Due to the decreased antioxidant function of Haptoglobin 2–2, diabetic individuals carrying this phenotype suffer from increased rates of oxidative stress and increased incidence of cardiovascular complications. In several epidemiological studies, oral supplementation with vitamin E proved therapeutic for this group, with a decrease in cardiovascular complications and improved high-density lipoprotein (HDL) function. Those findings led to the conclusion that vitamin E should be given to Haptoglobin 2–2 diabetic individuals as a preventive therapy against cardiovascular complications of diabetes.

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Ablation of Calcineurin Aβ Reveals Hyperlipidemia and Signaling ...

Conclusion: Calcineurin plays a r in metabolism. Results: Mice lacking calcineurin Aβ cause to grow metabolic complications. Background: Transplant patients treated with cyclosporine A, an inhibitor of calcineurin, again develop metabolic complications.
Source: http://www.jbc.org/content/288/5/3477

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Complications -Hyperlipidemia
Complications -Hyperlipidemia
Complications -Hyperlipidemia
Complications -Hyperlipidemia
Polyphenolic extract of Ichnocarpus frutescens modifies
Polyphenolic extract of Ichnocarpus frutescens modifies
Complications Of Hyperlipidemia by Nancy
Complications Of Hyperlipidemia by Nancy